ceesdekker.net for Dummies
ceesdekker.net for Dummies
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Making use of single-molecule optical and AFM imaging and drive-spectroscopy approaches, we find to unravel the mechanistic elements of the structure and dynamics of chromosomes. Our exploration passions consist of:
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, Groningen researchers present the outcomes of their efforts to produce labs far more sustainable and supply tricks for other labs.
Non-equilibrium folding of person DNA molecules recaptured as much as 1000 times in a good point out nanopore
2015, discovery that condensin is actually a highly adaptable protein construction; and first detection of DNA knots working with nanopores
Microbiology has only existed for the century, given that we started to research micro-organisms additional critically. I assumed nanobiology was an suitable expression, because all molecular biological appropriate interactions occur in the nanoscale: a protein is some nanometres in dimension, DNA is two nm thick.’
We form micro organism into varieties that deviate from their normal phenotype. Exclusively, I will display our ability to condition Dwell E. coli germs into novel shapes which include rectangles, squares, triangles and circles.
2000, discovery that nanotubes can carry amazing significant existing densities; solved the controversial concern of Digital transport by means of DNA molecules by measurements of insulating habits at The one molecule level; and demonstration of an AFM procedure for one-molecule manipulation of nanotubes
The rotors harness Vitality from the nanoscale drinking water and ion movement that is produced by a static chemical or electrochemical prospective gradient inside the nanopore, https://www.ceesdekker.net that are founded by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and run autonomously in physiological situations, suggesting ways to setting up Power-transducing motors at nanoscale interfaces.
Presently, we also understood that it ought to be attainable to utilize an individual semiconducting carbon nanotube to produce a transistor — and we set out to make it. We stretched person semiconducting nanotubes across metallic electrodes and made use of the fundamental silicon substrate being a gate electrode, setting up the basic a few-terminal structure of a area-effect transistor (Fig.
FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division
1999, very first measurement from the wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for just a new Luttinger description of interacting electrons in nanotubes
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Supercoiling-dependent DNA binding: quantitative modeling and programs to bulk and solitary-molecule experiments